Pavlova Anna
Research fellow
Research Interests
Мои интересы лежат преимущественно в сфере нейролингвистики. Мои предыдущие проекты были посвящены тому, как меняется процесс распознавания слов в зависимости от задачи, стоящей перед испытуемым. В настоящее время моя работа сконцентрирована на процессе речепорождения, а именно извлечения целевых слов из семантической памяти.
Publications:
2024
8.
Гояева, Д. Э.; Обухова, Т. С.; Овсянникова, Т. М.; Рытикова, А. М.; Джиоева, Ц. Г.; Павлова, А.; Николаева, А. Ю. (2024). Специфика оценивания фонематического слуха и его особенностей у детей с РАС. Новые Психологические Исследования, 4(1), 143-158. https://doi.org/10.51217/npsyresearch_2024_04_01_07
@article{Гояева2024,
title = {Специфика оценивания фонематического слуха и его особенностей у детей с РАС},
author = {Д.Э. Гояева and Т.С. Обухова and Т.М. Овсянникова and А.М. Рытикова and Ц.Г. Джиоева and А. Павлова and А.Ю. Николаева},
url = {https://megmoscow.ru/wp-content/uploads/pubs/10.51217_npsyresearch_2024_04_01_07.pdf},
doi = {10.51217/npsyresearch_2024_04_01_07},
issn = {2782-2184},
year = {2024},
date = {2024-04-03},
urldate = {2024-04-03},
journal = {Новые Психологические Исследования},
volume = {4},
number = {1},
pages = {143-158},
publisher = {Московский институт психоанализа},
abstract = {Расстройства аутистического спектра (РАС) характеризуются широким диапазоном когнитивных, социальных и коммуникативных нарушений. Одним из наиболее заметных проявлений РАС являются трудности в области речи и языка, которые могут серьезно ограничивать способность индивидов с РАС к эффективному общению и взаимодействию с окружающим миром. Проблема диагностики речевых нарушений у лиц с РАС усложняется тем, что многие существующие методики оценки не позволяют четко разделить речевые и языковые трудности от общего уровня интеллектуального развития, что может приводить к неточностям в интерпретации результатов. В данной работе мы сосредоточились на выявлении тех аспектов фонематического восприятия, которые могут быть оценены с минимальным влиянием интеллектуальных факторов. Для этого были использованы фонематические субтесты из комплексной диагностической батареи «КОРАБЛИК». Мы тщательно проанализировали результаты выполнения таких заданий, как «Повторение слов», «Повторение псевдослов», «Понимание существительных» и «Понимание глаголов», чтобы определить их способность отражать специфические речевые нарушения у детей с РАС. Результаты анализа показали наличие дефицита фонематического восприятия у детей с РАС, однако только результат задания «Повторение псевдослов» продемонстрировал стабильную корреляцию с речевыми нарушениями, не зависимо от уровня интеллекта участников. Данные результаты подчеркивают критическую необходимость в разработке и адаптации специализированных диагностических инструментов, которые были бы чувствительны к специфике речевых и языковых нарушений у лиц с РАС, но в то же время минимально зависели от их когнитивных способностей. Такие инструменты могли бы значительно улучшить точность диагностики и, как следствие, эффективность последующих коррекционных и образовательных программ для детей с РАС.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Расстройства аутистического спектра (РАС) характеризуются широким диапазоном когнитивных, социальных и коммуникативных нарушений. Одним из наиболее заметных проявлений РАС являются трудности в области речи и языка, которые могут серьезно ограничивать способность индивидов с РАС к эффективному общению и взаимодействию с окружающим миром. Проблема диагностики речевых нарушений у лиц с РАС усложняется тем, что многие существующие методики оценки не позволяют четко разделить речевые и языковые трудности от общего уровня интеллектуального развития, что может приводить к неточностям в интерпретации результатов. В данной работе мы сосредоточились на выявлении тех аспектов фонематического восприятия, которые могут быть оценены с минимальным влиянием интеллектуальных факторов. Для этого были использованы фонематические субтесты из комплексной диагностической батареи «КОРАБЛИК». Мы тщательно проанализировали результаты выполнения таких заданий, как «Повторение слов», «Повторение псевдослов», «Понимание существительных» и «Понимание глаголов», чтобы определить их способность отражать специфические речевые нарушения у детей с РАС. Результаты анализа показали наличие дефицита фонематического восприятия у детей с РАС, однако только результат задания «Повторение псевдослов» продемонстрировал стабильную корреляцию с речевыми нарушениями, не зависимо от уровня интеллекта участников. Данные результаты подчеркивают критическую необходимость в разработке и адаптации специализированных диагностических инструментов, которые были бы чувствительны к специфике речевых и языковых нарушений у лиц с РАС, но в то же время минимально зависели от их когнитивных способностей. Такие инструменты могли бы значительно улучшить точность диагностики и, как следствие, эффективность последующих коррекционных и образовательных программ для детей с РАС.
7.
Chernyshev, B. V.; Pavlova, A. A.; Rytikova, A. M.; Butorina, A. V.; Stroganova, T. A. (2024). Prolongation of Cerebral Activation in Response to a Stimulus as a Probable Mechanism of Associative Plasticity during Semantic Learning. Neuroscience and Behavioral Physiology, 54(3), 434-447. https://doi.org/10.1007/s11055-024-01610-0
@article{Chernyshev2024,
title = {Prolongation of Cerebral Activation in Response to a Stimulus as a Probable Mechanism of Associative Plasticity during Semantic Learning},
author = {B. V. Chernyshev and A. A. Pavlova and A. M. Rytikova and A. V. Butorina and T. A. Stroganova},
url = {https://megmoscow.ru/wp-content/uploads/pubs/10.1007_s11055-024-01610-0.pdf},
doi = {10.1007/s11055-024-01610-0},
issn = {1573-899X},
year = {2024},
date = {2024-03-00},
urldate = {2024-03-00},
journal = {Neuroscience and Behavioral Physiology },
volume = {54},
number = {3},
pages = {434-447},
publisher = {Springer Science and Business Media LLC},
abstract = {Remembering the meanings of new spoken words is believed to occur as a result of associative learning. For example, this is how words denoting movements can be compared with their corresponding motor acts. Synaptic plasticity is known to develop in the brain when the activity of the cellular ensembles representing associated events coincides in time. However, in reality, such associations can develop when there is a significant time gap between the events to be associated, violating the conditions required for the occurrence of synaptic plasticity. We suggested that the conditions required for the development of synaptic plasticity in the brain can be created if the activity of neural representations is prolonged in time such that the required overlap in time at the level of neural ensembles is achieved. To test this assumption, we recorded magnetoencephalograms from voluntary participants during the development of associations between pseudowords and movements of the four limbs. The results obtained here show that there is indeed a significant prolongation of stimulus-induced auditory-verbal activation when new associations develop. Thus, during the development of an association, conditions can be created in the brain for the development of Hebbian plasticity, even if the associated events are separated in time.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Remembering the meanings of new spoken words is believed to occur as a result of associative learning. For example, this is how words denoting movements can be compared with their corresponding motor acts. Synaptic plasticity is known to develop in the brain when the activity of the cellular ensembles representing associated events coincides in time. However, in reality, such associations can develop when there is a significant time gap between the events to be associated, violating the conditions required for the occurrence of synaptic plasticity. We suggested that the conditions required for the development of synaptic plasticity in the brain can be created if the activity of neural representations is prolonged in time such that the required overlap in time at the level of neural ensembles is achieved. To test this assumption, we recorded magnetoencephalograms from voluntary participants during the development of associations between pseudowords and movements of the four limbs. The results obtained here show that there is indeed a significant prolongation of stimulus-induced auditory-verbal activation when new associations develop. Thus, during the development of an association, conditions can be created in the brain for the development of Hebbian plasticity, even if the associated events are separated in time.
2023
6.
Гояева, Д. Э.; Обухова, Т. С.; Овсянникова, Т. М.; Рытикова, А. М.; Павлова, А. А.; Джиоева, Ц. Г.; Кокоев, Т. И.; Николаева, А. Ю. (2023). Особенности фонематического восприятия речи у обучающихся с билингвизмом. Экспериментальная психология, 16(4), 129-142. https://doi.org/10.17759/exppsy.2023160409
@article{Goyaeva2023b,
title = {Особенности фонематического восприятия речи у обучающихся с билингвизмом},
author = {Гояева, Д.Э. and Обухова, Т.С. and Овсянникова, Т.М. and Рытикова, А.М. and Павлова, А.А. and Джиоева, Ц.Г. and Кокоев, Т.И. and Николаева, А.Ю.},
url = {https://megmoscow.ru/wp-content/uploads/pubs/10.17759_exppsy.2023160409.pdf},
doi = {10.17759/exppsy.2023160409},
issn = {2311-7036},
year = {2023},
date = {2023-12-01},
urldate = {2023-12-01},
journal = {Экспериментальная психология},
volume = {16},
number = {4},
pages = {129-142},
publisher = {Московский государственный психолого-педагогический университет},
abstract = {В Российской Федерации используется, по разным источникам, от 277 до 295 различных языков, что делает очень важным вопрос оценки влияния билингвизма на восприятие речи, например в контексте школьного обучения. Существуют противоречивые данные о том, как дети, растущие в двуязычной среде, распознают отдельные фонемы. В данной работе мы сравнили восприятие фонем русского языка на слух у детей младшего и среднего школьного возраста из моноязычной (русскоязычной) и двуязычной (русскоязычной и осетиноязычной) среды при помощи речевого теста «КОРАБЛИК» («Клиническая оценка развития базовых лингвистических компетенций») и психофизической задачи на различение слов в шуме. Было обнаружено, что двуязычные дети хуже повторяют псевдослова и распознают фонемы в стационарном шуме, что говорит о наличии значимых затруднений, но проявляющихся только в ситуациях нового/затрудненного восприятия. Причины затруднений могут быть связаны с тем, что у детей, растущих в двуязычной среде, значительно шире перечень фонем, которые необходимо распознавать, чем у детей, растущих в моноязычной среде. Это может приводить к сниженному распознаванию речи на языке обучения и, соответственно, возможному снижению качества обучения.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
В Российской Федерации используется, по разным источникам, от 277 до 295 различных языков, что делает очень важным вопрос оценки влияния билингвизма на восприятие речи, например в контексте школьного обучения. Существуют противоречивые данные о том, как дети, растущие в двуязычной среде, распознают отдельные фонемы. В данной работе мы сравнили восприятие фонем русского языка на слух у детей младшего и среднего школьного возраста из моноязычной (русскоязычной) и двуязычной (русскоязычной и осетиноязычной) среды при помощи речевого теста «КОРАБЛИК» («Клиническая оценка развития базовых лингвистических компетенций») и психофизической задачи на различение слов в шуме. Было обнаружено, что двуязычные дети хуже повторяют псевдослова и распознают фонемы в стационарном шуме, что говорит о наличии значимых затруднений, но проявляющихся только в ситуациях нового/затрудненного восприятия. Причины затруднений могут быть связаны с тем, что у детей, растущих в двуязычной среде, значительно шире перечень фонем, которые необходимо распознавать, чем у детей, растущих в моноязычной среде. Это может приводить к сниженному распознаванию речи на языке обучения и, соответственно, возможному снижению качества обучения.
5.
Чернышев, Б. В.; Павлова, А. А.; Рытикова, А. М.; Буторина, А. В.; Строганова, Т. А. (2023). Продление мозговой активации в ответ на стимул как вероятный механизм ассоциативной пластичности при семантическом научении. Журнал высшей нервной деятельности им. И.П.Павлова, 73(6), 764-784. https://doi.org/10.31857/s0044467723060035
@article{Chernyshev2023,
title = {Продление мозговой активации в ответ на стимул как вероятный механизм ассоциативной пластичности при семантическом научении},
author = {Б.В. Чернышев and А.А. Павлова and А.М. Рытикова and А.В. Буторина and Т.А. Строганова},
url = {https://megmoscow.ru/wp-content/uploads/pubs/10.31857_s0044467723060035.pdf},
doi = {10.31857/s0044467723060035},
issn = {0044-4677},
year = {2023},
date = {2023-11-01},
urldate = {2023-11-01},
journal = {Журнал высшей нервной деятельности им. И.П.Павлова},
volume = {73},
number = {6},
pages = {764-784},
publisher = {Российская академия наук},
abstract = {Считается, что запоминание смысла новых слов речи происходит благодаря ассоциативному обучению. Например, именно так слова, обозначающие движения, могут сопоставляться с соответствующими моторными актами. Известно, что синаптическая пластичность в мозге развивается при условии совпадения во времени активности клеточных ансамблей, репрезентирующих ассоциируемые события. Однако в реальности при выработке подобных ассоциаций возможен значительный разрыв во времени между ассоциируемыми событиями, нарушающий условия возникновения синаптической пластичности. Мы предположили, что необходимые условия для развития синаптической пластичности в мозге могут создаваться благодаря тому, что активность нейронных репрезентаций продлевается во времени, и тем самым обеспечивается требуемое перекрытие во времени на уровне нейронных ансамблей. Чтобы проверить это предположение, мы регистрировали магнитоэнцефалограмму у добровольных участников во время выработки ассоциаций между псевдословами и движениями четырьмя конечностями. Результаты исследования показывают, что при выработке новых ассоциаций действительно происходит значимое удлинение слухоречевой активации, вызванной стимулом. Таким образом, во время выработки ассоциации в мозге действительно могут создаваться условия для развития Хеббовской пластичности, даже если ассоциируемые события разнесены во времени.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Считается, что запоминание смысла новых слов речи происходит благодаря ассоциативному обучению. Например, именно так слова, обозначающие движения, могут сопоставляться с соответствующими моторными актами. Известно, что синаптическая пластичность в мозге развивается при условии совпадения во времени активности клеточных ансамблей, репрезентирующих ассоциируемые события. Однако в реальности при выработке подобных ассоциаций возможен значительный разрыв во времени между ассоциируемыми событиями, нарушающий условия возникновения синаптической пластичности. Мы предположили, что необходимые условия для развития синаптической пластичности в мозге могут создаваться благодаря тому, что активность нейронных репрезентаций продлевается во времени, и тем самым обеспечивается требуемое перекрытие во времени на уровне нейронных ансамблей. Чтобы проверить это предположение, мы регистрировали магнитоэнцефалограмму у добровольных участников во время выработки ассоциаций между псевдословами и движениями четырьмя конечностями. Результаты исследования показывают, что при выработке новых ассоциаций действительно происходит значимое удлинение слухоречевой активации, вызванной стимулом. Таким образом, во время выработки ассоциации в мозге действительно могут создаваться условия для развития Хеббовской пластичности, даже если ассоциируемые события разнесены во времени.
4.
Pavlova, Anna; Tyulenev, Nikita; Tretyakova, Vera; Skavronskaya, Valeriya; Nikolaeva, Anastasia; Prokofyev, Andrey; Stroganova, Tatiana; Chernyshev, Boris (2023). Learning of new associations invokes a major change in modulations of cortical beta oscillations in human adults. Psychophysiology, 60, e14284. https://doi.org/10.1111/psyp.14284
@article{Pavlova2023,
title = {Learning of new associations invokes a major change in modulations of cortical beta oscillations in human adults},
author = {Anna Pavlova and Nikita Tyulenev and Vera Tretyakova and Valeriya Skavronskaya and Anastasia Nikolaeva and Andrey Prokofyev and Tatiana Stroganova and Boris Chernyshev},
url = {https://megmoscow.ru/wp-content/uploads/pubs/10.1111_psyp.14284.pdf},
doi = {10.1111/psyp.14284},
issn = {1469-8986},
year = {2023},
date = {2023-08-00},
urldate = {2023-08-00},
journal = {Psychophysiology},
volume = {60},
issue = {8},
pages = {e14284},
publisher = {Wiley},
abstract = {Large-scale cortical beta (β) oscillations were implicated in the learning processes, but their exact role is debated. We used MEG to explore the dynamics of movement-related β-oscillations while 22 adults learned, through trial and error, novel associations between four auditory pseudowords and movements of four limbs. As learning proceeded, spatial–temporal characteristics of β-oscillations accompanying cue-triggered movements underwent a major transition. Early in learning, widespread suppression of β-power occurred long before movement initiation and sustained throughout the whole behavioral trial. When learning advanced and performance reached asymptote, β-suppression after the initiation of correct motor response was replaced by a rise in β-power mainly in the prefrontal and medial temporal regions of the left hemisphere. This post-decision β-power predicted trial-by-trial response times (RT) at both stages of learning (before and after the rules become familiar), but with different signs of interaction. When a subject just started to acquire associative rules and gradually improved task performance, a decrease in RT correlated with the increase in the post-decision β-band power. When the participants implemented the already acquired rules, faster (more confident) responses were associated with the weaker post-decision β-band synchronization. Our findings suggest that maximal beta activity is pertinent to a distinct stage of learning and may serve to strengthen the newly learned association in a distributed memory network.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Large-scale cortical beta (β) oscillations were implicated in the learning processes, but their exact role is debated. We used MEG to explore the dynamics of movement-related β-oscillations while 22 adults learned, through trial and error, novel associations between four auditory pseudowords and movements of four limbs. As learning proceeded, spatial–temporal characteristics of β-oscillations accompanying cue-triggered movements underwent a major transition. Early in learning, widespread suppression of β-power occurred long before movement initiation and sustained throughout the whole behavioral trial. When learning advanced and performance reached asymptote, β-suppression after the initiation of correct motor response was replaced by a rise in β-power mainly in the prefrontal and medial temporal regions of the left hemisphere. This post-decision β-power predicted trial-by-trial response times (RT) at both stages of learning (before and after the rules become familiar), but with different signs of interaction. When a subject just started to acquire associative rules and gradually improved task performance, a decrease in RT correlated with the increase in the post-decision β-band power. When the participants implemented the already acquired rules, faster (more confident) responses were associated with the weaker post-decision β-band synchronization. Our findings suggest that maximal beta activity is pertinent to a distinct stage of learning and may serve to strengthen the newly learned association in a distributed memory network.
2019
3.
Pavlova, Anna A.; Butorina, Anna V.; Nikolaeva, Anastasia Y.; Prokofyev, Andrey O.; Ulanov, Maxim A.; Bondarev, Denis P.; Stroganova, Tatiana A. (2019). Effortful verb retrieval from semantic memory drives beta suppression in mesial frontal regions involved in action initiation. Human Brain Mapping, 40(12), 3669-3681. https://doi.org/10.1002/hbm.24624
@article{Pavlova2019b,
title = {Effortful verb retrieval from semantic memory drives beta suppression in mesial frontal regions involved in action initiation},
author = {Anna A. Pavlova and Anna V. Butorina and Anastasia Y. Nikolaeva and Andrey O. Prokofyev and Maxim A. Ulanov and Denis P. Bondarev and Tatiana A. Stroganova},
url = {https://onlinelibrary.wiley.com/doi/epdf/10.1002/hbm.24624},
doi = {10.1002/hbm.24624},
issn = {1097-0193},
year = {2019},
date = {2019-08-15},
urldate = {2019-08-15},
journal = {Human Brain Mapping},
volume = {40},
number = {12},
pages = {3669-3681},
publisher = {Wiley},
abstract = {The contribution of the motor cortex to the semantic retrieval of verbs remains a subject of debate in neuroscience. Here, we examined whether additional engagement of the cortical motor system was required when access to verbs semantics was hindered during a verb generation task. We asked participants to produce verbs related to presented noun cues that were either strongly associated with a single verb to prompt fast and effortless verb retrieval, or were weakly associated with multiple verbs and more difficult to respond to. Using power suppression of magnetoencephalography beta oscillations (15–30 Hz) as an index of cortical activation, we performed a whole‐brain analysis in order to identify the cortical regions sensitive to the difficulty of verb semantic retrieval. Highly reliable suppression of beta oscillations occurred 250 ms after the noun cue presentation and was sustained until the onset of verbal response. This was localized to multiple cortical regions, mainly in the temporal and frontal lobes of the left hemisphere. Crucially, the only cortical regions where beta suppression was sensitive to the task difficulty, were the higher order motor areas on the medial and lateral surfaces of the frontal lobe. Stronger activation of the premotor cortex and supplementary motor area accompanied the effortful verb retrieval and preceded the preparation of verbal responses for more than 500 ms, thus, overlapping with the time window of verb retrieval from semantic memory. Our results suggest that reactivation of verb‐related motor plans in higher order motor circuitry promotes the semantic retrieval of target verbs.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The contribution of the motor cortex to the semantic retrieval of verbs remains a subject of debate in neuroscience. Here, we examined whether additional engagement of the cortical motor system was required when access to verbs semantics was hindered during a verb generation task. We asked participants to produce verbs related to presented noun cues that were either strongly associated with a single verb to prompt fast and effortless verb retrieval, or were weakly associated with multiple verbs and more difficult to respond to. Using power suppression of magnetoencephalography beta oscillations (15–30 Hz) as an index of cortical activation, we performed a whole‐brain analysis in order to identify the cortical regions sensitive to the difficulty of verb semantic retrieval. Highly reliable suppression of beta oscillations occurred 250 ms after the noun cue presentation and was sustained until the onset of verbal response. This was localized to multiple cortical regions, mainly in the temporal and frontal lobes of the left hemisphere. Crucially, the only cortical regions where beta suppression was sensitive to the task difficulty, were the higher order motor areas on the medial and lateral surfaces of the frontal lobe. Stronger activation of the premotor cortex and supplementary motor area accompanied the effortful verb retrieval and preceded the preparation of verbal responses for more than 500 ms, thus, overlapping with the time window of verb retrieval from semantic memory. Our results suggest that reactivation of verb‐related motor plans in higher order motor circuitry promotes the semantic retrieval of target verbs.
2017
2.
Pavlova, Anna A.; Butorina, Anna V.; Nikolaeva, Anastasia Y.; Prokofyev, Andrey O.; Ulanov, Maxim A.; Stroganova, Tatiana A. (2017). Not all reading is alike: task modulation of magnetic evoked response to visual word. Psychology in Russia: State of the art, 10(3), 190-205. https://doi.org/10.11621/pir.2017.0313
@article{nokey,
title = {Not all reading is alike: task modulation of magnetic evoked response to visual word},
author = {Pavlova, Anna A. and Butorina, Anna V. and Nikolaeva, Anastasia Y. and Prokofyev, Andrey O. and Ulanov, Maxim A. and Stroganova, Tatiana A.},
doi = {10.11621/pir.2017.0313},
year = {2017},
date = {2017-12-00},
journal = {Psychology in Russia: State of the art},
volume = {10},
number = {3},
pages = {190-205},
publisher = {Russian Psychology Society},
abstract = {Background.
Previous studies have shown that brain response to a written word depends on the task: whether the word is a target in a version of lexical decision task or should be read silently. Although this effect has been interpreted as an evidence for an interaction between word recognition processes and task demands, it also may be caused by greater attention allocation to the target word.
Objective.
We aimed to examine the task effect on brain response evoked by non-target written words.
Design.
Using MEG and magnetic source imaging, we compared spatial-temporal pattern of brain response elicited by a noun cue when it was read silently either without additional task (SR) or with a requirement to produce an associated verb (VG).
Results.
The task demands penetrated into early (200-300 ms) and late (500-800 ms) stages of a word processing by enhancing brain response under VG versus SR condition. The cortical sources of the early response were localized to bilateral inferior occipitotem-poral and anterior temporal cortex suggesting that more demanding VG task required elaborated lexical-semantic analysis. The late effect was observed in the associative auditory areas in middle and superior temporal gyri and in motor representation of articulators. Our results suggest that a remote goal plays a pivotal role in enhanced recruitment of cortical structures underlying orthographic, semantic and sensorimotor dimensions of written word perception from the early processing stages. Surprisingly, we found that to full a more challenging goal the brain progressively engaged resources of the right hemisphere throughout all stages of silent reading. Conclusion. Our study demonstrates that a deeper processing of linguistic input amplies activation of brain areas involved in integration of speech perception and pro-duction. This is consistent with theories that emphasize the role of sensorimotor integration in speech understanding.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Background.
Previous studies have shown that brain response to a written word depends on the task: whether the word is a target in a version of lexical decision task or should be read silently. Although this effect has been interpreted as an evidence for an interaction between word recognition processes and task demands, it also may be caused by greater attention allocation to the target word.
Objective.
We aimed to examine the task effect on brain response evoked by non-target written words.
Design.
Using MEG and magnetic source imaging, we compared spatial-temporal pattern of brain response elicited by a noun cue when it was read silently either without additional task (SR) or with a requirement to produce an associated verb (VG).
Results.
The task demands penetrated into early (200-300 ms) and late (500-800 ms) stages of a word processing by enhancing brain response under VG versus SR condition. The cortical sources of the early response were localized to bilateral inferior occipitotem-poral and anterior temporal cortex suggesting that more demanding VG task required elaborated lexical-semantic analysis. The late effect was observed in the associative auditory areas in middle and superior temporal gyri and in motor representation of articulators. Our results suggest that a remote goal plays a pivotal role in enhanced recruitment of cortical structures underlying orthographic, semantic and sensorimotor dimensions of written word perception from the early processing stages. Surprisingly, we found that to full a more challenging goal the brain progressively engaged resources of the right hemisphere throughout all stages of silent reading. Conclusion. Our study demonstrates that a deeper processing of linguistic input amplies activation of brain areas involved in integration of speech perception and pro-duction. This is consistent with theories that emphasize the role of sensorimotor integration in speech understanding.
Previous studies have shown that brain response to a written word depends on the task: whether the word is a target in a version of lexical decision task or should be read silently. Although this effect has been interpreted as an evidence for an interaction between word recognition processes and task demands, it also may be caused by greater attention allocation to the target word.
Objective.
We aimed to examine the task effect on brain response evoked by non-target written words.
Design.
Using MEG and magnetic source imaging, we compared spatial-temporal pattern of brain response elicited by a noun cue when it was read silently either without additional task (SR) or with a requirement to produce an associated verb (VG).
Results.
The task demands penetrated into early (200-300 ms) and late (500-800 ms) stages of a word processing by enhancing brain response under VG versus SR condition. The cortical sources of the early response were localized to bilateral inferior occipitotem-poral and anterior temporal cortex suggesting that more demanding VG task required elaborated lexical-semantic analysis. The late effect was observed in the associative auditory areas in middle and superior temporal gyri and in motor representation of articulators. Our results suggest that a remote goal plays a pivotal role in enhanced recruitment of cortical structures underlying orthographic, semantic and sensorimotor dimensions of written word perception from the early processing stages. Surprisingly, we found that to full a more challenging goal the brain progressively engaged resources of the right hemisphere throughout all stages of silent reading. Conclusion. Our study demonstrates that a deeper processing of linguistic input amplies activation of brain areas involved in integration of speech perception and pro-duction. This is consistent with theories that emphasize the role of sensorimotor integration in speech understanding.
1.
Butorina, Anna V.; Pavlova, Anna A.; Nikolaeva, Anastasia Y.; Prokofyev, Andrey O.; Bondarev, Denis P.; Stroganova, Tatiana A. (2017). Simultaneous Processing of Noun Cue and to-be-Produced Verb in Verb Generation Task: Electromagnetic Evidence. Frontiers in Human Neuroscience, 11, 279. https://doi.org/10.3389/fnhum.2017.00279
@article{Butorina2017,
title = {Simultaneous Processing of Noun Cue and to-be-Produced Verb in Verb Generation Task: Electromagnetic Evidence},
author = {Anna V. Butorina and Anna A. Pavlova and Anastasia Y. Nikolaeva and Andrey O. Prokofyev and Denis P. Bondarev and Tatiana A. Stroganova},
url = {https://megmoscow.ru/wp-content/uploads/pubs/10.3389_fnhum.2017.00279.pdf},
doi = {10.3389/fnhum.2017.00279},
issn = {1662-5161},
year = {2017},
date = {2017-05-30},
urldate = {2017-05-30},
journal = {Frontiers in Human Neuroscience},
volume = {11},
pages = {279},
publisher = {Frontiers Media SA},
abstract = {A long-standing but implicit assumption is that words strongly associated with a presented cue are automatically activated in the memory through rapid spread of activation within brain semantic networks. The current study was aimed to provide direct evidence of such rapid access to words’ semantic representations and to investigate its neural sources using magnetoencephalography (MEG) and distributed source localization technique. Thirty-three neurotypical subjects underwent the MEG recording during verb generation task, which was to produce verbs related to the presented noun cues. Brain responses evoked by the noun cues were examined while manipulating the strength of association between the noun and the potential verb responses. The strong vs. weak noun-verb association led to a greater noun-related neural response at 250–400 ms after cue onset, and faster verb production. The cortical sources of the differential response were localized in left temporal pole, previously implicated in semantic access, and left ventrolateral prefrontal cortex (VLPFC), thought to subserve controlled semantic retrieval. The strength of the left VLPFC’s response to the nouns with strong verb associates was positively correlated to the speed of verbs production. Our findings empirically validate the theoretical expectation that in case of a strongly connected noun-verb pair, successful access to target verb representation may occur already at the stage of lexico-semantic analysis of the presented noun. Moreover, the MEG results suggest that contrary to the previous conclusion derived from fMRI studies left VLPFC supports selection of the target verb representations, even if they were retrieved from semantic memory rapidly and effortlessly. The discordance between MEG and fMRI findings in verb generation task may stem from different modes of neural activation captured by phase-locked activity in MEG and slow changes of blood-oxygen-level-dependent (BOLD) signal in fMRI.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
A long-standing but implicit assumption is that words strongly associated with a presented cue are automatically activated in the memory through rapid spread of activation within brain semantic networks. The current study was aimed to provide direct evidence of such rapid access to words’ semantic representations and to investigate its neural sources using magnetoencephalography (MEG) and distributed source localization technique. Thirty-three neurotypical subjects underwent the MEG recording during verb generation task, which was to produce verbs related to the presented noun cues. Brain responses evoked by the noun cues were examined while manipulating the strength of association between the noun and the potential verb responses. The strong vs. weak noun-verb association led to a greater noun-related neural response at 250–400 ms after cue onset, and faster verb production. The cortical sources of the differential response were localized in left temporal pole, previously implicated in semantic access, and left ventrolateral prefrontal cortex (VLPFC), thought to subserve controlled semantic retrieval. The strength of the left VLPFC’s response to the nouns with strong verb associates was positively correlated to the speed of verbs production. Our findings empirically validate the theoretical expectation that in case of a strongly connected noun-verb pair, successful access to target verb representation may occur already at the stage of lexico-semantic analysis of the presented noun. Moreover, the MEG results suggest that contrary to the previous conclusion derived from fMRI studies left VLPFC supports selection of the target verb representations, even if they were retrieved from semantic memory rapidly and effortlessly. The discordance between MEG and fMRI findings in verb generation task may stem from different modes of neural activation captured by phase-locked activity in MEG and slow changes of blood-oxygen-level-dependent (BOLD) signal in fMRI.